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KMID : 0370219980420030312
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Yakhak Hoeji
1998 Volume.42 No. 3 p.312 ~ p.318
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Antioxidative Effects of the Rhizome of Rhodiola Sachalinensis
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류광열/Ryu KY
강원식/김영호/장해동/홍진태/유환수/윤여표/Kang WS/Kim YH/Jang HD/Hong JT/Yoo HS/Yun YP
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Abstract
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Ihe purpose of this study was to determine the antioxidative effects of Rhodiola sachalinensis. Rhodiola methanol extract was fractionated sequentially with dichlorometha ne and butanol. Each Rhodiola fraction (water, MeOH, BuOH and CH2Cl2 fractions) showed the potent superoxide dismutase (SOD) activity, and had inhibitory effects on peroxide value of linoleic acid (40-57%) and lipid peroxidation (47-70%). In Fe2+/ascorbate system-induced rat liver microsome. Rhodiola methanol extract also recovered carbon tetrachloride-induced decrease in SOD by 42% and catalase activities by 50%, and had inhibitory effects (54%) on carbon tetrachloride-induced lipid peroxidation in rat liver microsome. These results suggest that Rhodiola sachalinensis has the antioxidative effects.
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